

The city's population is 215,006 as of the 2020 census, making it Alabama's most populous city. The National Trust for Historic Preservation named Huntsville to its "America's Dozen Distinctive Destinations for 2010" list. NASA's Marshall Space Flight Center, the United States Army Aviation and Missile Command, and most recently the FBI’s operational support headquarters all came to be located at nearby Redstone Arsenal. After the war, additional research was conducted at Redstone Arsenal on rockets, followed by adaptations to use them for space exploration. During the war, the Army established Redstone Arsenal near here with a chemical weapons plant, and nearby related facilities. Its major growth has taken place since World War II. The city developed across nearby hills north of the Tennessee River, adding textile mills in the late nineteenth century. When Alabama was admitted as a state in 1819, Huntsville was designated for a year as the first capital, before that was moved to more central settlements.

Located within the Mississippi Territory, Huntsville was founded by European Americans in 1805 and became an incorporated town in 1811. Extending west into neighboring Limestone County and south into Morgan County, Huntsville has become the largest city in the state.

Huntsville is a city in the Appalachian region of northern Alabama and is the county seat of Madison County.
